Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Reactions of Carbene Conjugated with 1-Azaazulene Moiety : Additions of 3-(2-Chloro-1-azaazulenyl)methylene with cis- and trans-Stibenes and p-Substituted Styrenes to Form 3-Cyclopropyl-1-azaazulenes
Katsuhiro SAITOHiroshi FUSHIHARAKensuke TAKAHASHINoritaka ABE
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1993 Volume 41 Issue 4 Pages 752-754

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Abstract
The addition reactions of 3-(2-chloro-1-azaazulenyl)methylene with cis- and trans-stilbenes proceeded in a stereospecific manner to afford the corresponding cyclopropane derivatives. The substitution effects on the relative rate ratio of the addition reactions of the carbene with styrenes having various substituents on the p-positions were measured to investigate the electronic nature of carbene.
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© The Pharmaceutical Society of Japan
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